Candidacidal activity of Crohn's disease neutrophils.
نویسندگان
چکیده
منابع مشابه
Inhibition by sulfonamides of the candidacidal activity of human neutrophils.
Sulfonamides reduced substantially the ability of normal human neutrophils to kill strains of Candida albicans and Candida tropicalis, and impaired to a lesser extent their activity against Staphylococcus aureus 502A and Serratia marcescens. Sulfonamides also inhibited (a) iodination of Candida cells by normal neutrophils; (b) candidacidal activity in cell-free systems containing purified human...
متن کاملFunctional aspects of a second mechanism of candidacidal activity by human neutrophils.
We tested the ability of human neutrophils to kill five Candida species and the yeast Torulopsis glabrata. C. parapsilosis and C. pseudotropicalis were found to be killed readily by normal and myeloperoxidase-deficient neutrophils and were selected to probe the myeloperoxidase-independent fungicidal mechanisms of the neutrophil. These organisms were killed with relatively normal (C. parapsilosi...
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We here report a case of a young man who presented to his general practitioner with diarrhea. Inflammatory bowel disease was suspected and a colonoscopy showed aphthous lesions suggestive of Crohns' disease but biopsies revealed eggs of Enterobius vermicularis. When treated for this parasite, his symptoms were alleviated and a followup colonoscopy revealed a normal colon and distal ileum. Enter...
متن کاملComparison of candidacidal and candidastatic activities of human neutrophils.
Disruption of neutrophils causes the release of a cytoplasmic protein which can inhibit the growth of Candida albicans without killing the organisms. The present study was undertaken with a combined system in which candidacidal and candidastatic activities of human neutrophils could be compared. In this system it was found that disruption of either half or all of the neutrophils in the samples ...
متن کاملChanges of Small Bowel Peristalsis in Patients with Crohns Disease
Purpose: MR enterography (MRE) is one of the mainstays in the evaluation of Crohns disease (CD). A wide variety of studies have attempted to improve the sensitivity and specificity of MRE, all focusing on the evaluation of static images [1]. MRE however allows not only the static display of morphology, but can be combined with ultrafast scanning techniques (cineMRE) for analysis of bowel motili...
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ژورنال
عنوان ژورنال: Gut
سال: 1991
ISSN: 0017-5749
DOI: 10.1136/gut.32.1.55